PDA aneurysms make up 2% of all splanchnic aneurysms and are associated with a rupture risk as high as 65%. The mortality rate for a ruptured PDA aneurysm is around 50%. Currently, the SVS recommends treatment of all PDA aneurysms regardless of their size. This video describes two interesting cases comparing endovascular and open treatment for pancreaticoduodenal artery or PDA aneurysms. The two cases were treated differently based off of the anatomy of the aneurysms. It is imperative to clearly delineate the anatomy of the aneurysm and its feeding and egress vessels to determine whether an endovascular or an open approach should be utilized.