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Clinical Correlation Of SFA Disease And Symptoms
Brandon Ruggeberg, BA
1, Justin M. Robbins, MD
2, Natalie A. Marks, MD
3, Enrico Ascher, MD
3, Anil P. Hingorani, MD
3.
1Universidad Autónoma de Guadalajara, Guadalajara, Mexico,
2Wright State University, Dayton, OH, USA,
3NYU Langone- Brooklyn, Brooklyn, NY, USA.
Objectives. We noted a correlation between SFA location and symptoms in patients undergoing angioplasties. Searching the literature, we found an absence on this topic, leading us to search for any association between the location of SFA disease and severity of symptoms.
Methods. A retrospective review of all SFA angioplasties at a single institution was done from 2014 to 2022. Patients were excluded if the ipsilateral lower extremity had either a prior revascularization procedure or PAD proximal to the SFA. Popliteal and tibial disease were not assessed. Angioplasties were categorized consecutively into proximal, middle, or distal one-third of the SFA, by reviewing angiograms for the most proximal SFA lesion. PAD was further assessed as occlusion or the percent stenosis. Chart review was then performed to collect patients' symptoms, claudication and CLTI. Patients' characteristics, rate of diabetes, laterality of lower extremity, age, and sex were also analyzed. Fisher’s Exact Test and Student’s t-test were employed for analysis of the data.
Results. Table 1. summarizes the results of the 228 procedures identified. The relation between SFA location and claudication or CLTI was not significant (p = 0.32). The mean claudication (measured in number of blocks able to walk) of proximal, middle, and distal lesions was 1.2 (SD = 0.74), 1.8 (SD = 0.96), and 2.0 (SD = 1.4), respectively. The mean claudication of the mid and distal lesions was higher when compared to proximal lesions (t (99) = -3.07, p = 0.001). The rate of occlusion was higher in the proximal category when compared to middle and distal SFA disease (p = 0.029). No difference was observed in the incidence of diabetes (p = 0.34), or the distribution of lower extremity side (p = .11), sex (p = 0.67), and age (p = 0.17) between groups.
Conclusion. No correlation was observed between the location of SFA disease and claudication versus CLTI. However, more severe claudication and a higher rate of occlusion was reported in proximal SFA lesions than middle and distal SFA disease, seemingly highlighting a difference in the correlation of symptoms and proximal, middle, or distal SFA disease.
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