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The Impact Of Multiparity On Venous Insufficiency
Olga Bakayev, MD
1, Emilia Kalutskaya, BS
2, Crystal McLeod, BS
3, Rielyn Booker, BS
4, Natalie Marks, MD
1, Enrico Ascher, MD
1, Anil Hingorani, MD
5.
1Total Vascular Care, Brooklyn, NY, USA,
2Wright State University, Dayton, OH, USA,
3University of British Colombia, Vancouver, BC, Canada,
4Avalon University School of Medicine, Willemstad, Curaçao,
5NYU Langone, Brooklyn, NY, USA.
OBJECTIVES: This study evaluates the impact of multiparity on venous insufficiency among women, addressing gaps¹ and controversies² in the existing literature.
METHODS: A retrospective, non-randomized, observational study was conducted on female patients aged 18 and older who underwent venous mapping duplex at a single outpatient laboratory (OBL) from January 19, 2020, to January 19, 2023. 104 patients agreed to participate in a telephone survey. The survey content pertained to demographics, obstetric history,
and vascular disease risk factors. We collected the most recent venous mapping results from medical records and used linear regression analysis in R software to assess the impact of the number of pregnancies on Great Saphenous Vein (GSV) reflux. The study was approved by the Institutional Review Board.
RESULTS: Among the participants, 27.88% (29 women) exhibited bilateral GSV reflux in the latest venous mapping. Linear regression analysis revealed an increase in reflux severity by approximately 400.5 for each additional pregnancy, although this association was not statistically significant (p = 0.191218). The low R-squared value (0.02768) suggests that other factors, such as age, BMI, and genetic predispositions, may also influence reflux severity. The mean age of the cohort was 63 years (range 29-93 years), with an average BMI of 31.8.
CONCLUSIONS: Multiparity does not appear to be a significant predictor of GSV reflux based on our findings. Considerations for future research include expanding the sample size to enhance the robustness of results and potentially exploring the impact of additional variables on reflux severity.
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