Differences between males and females with intermittent claudication undergoing percutaneous angioplasty in the greater New York Vascular Quality Initiative
Patrick T. Jasinski, MD, Nicos Labropoulos, PhD, Apostolos K. Tassiopoulos, MD, Angela A. Kokkosis, MD.
Stony Brook Medicine, Stony Brook, NY, USA.
OBJECTIVES: The purpose of this study was to assess the differences in presentation and outcomes between males and females who underwent percutaneous angioplasty (PTA) for intermittent claudication (IC) in the regional Vascular Quality Initiative (VQI).
METHODS: A retrospective analysis of males and females from the greater New York area VQI was performed from January 2011 to January 2015. Inclusion criteria were all males and females treated with PTA for TASC A and TASC B lesions in the superficial femoral artery. Excluded were all peripheral vascular interventions (stents, cryoplasty, cutting balloon, atherectomy) other than PTA, TASC C and TASC D lesions, patients treated for more than 1 artery, as well as asymptomatic patients.
RESULTS: Analysis included 112 patients. Of those, 66 were males and 46 were females. Mean ages were 65.82 ± 9.19 and 69.46 ± 10.94 years respectively (P = .0007). Coronary artery disease (P = .047) and previous history of CABG/PCI (P = .014) was identified more frequently in males. There was no difference in smoking status, hypertension, congestive heart failure, and chronic obstructive pulmonary disease between both groups. Females were less likely to be treated for diabetes mellitus (56.1% males vs. 37% females, P = .056). Preoperative ankle-brachial indices were greater in males (0.7 ± 0.17 vs. 0.58 ± 0.16; P = .0003). Marked improvement of ABI’s was appreciated after treatment (0.94 ± 0.17, N = 19 vs. 0.89 ± 0.17, N = 13), however without statistical significant difference between both groups.
CONCLUSIONS: There remains to be a difference between in presentation between males and females with IC in the greater New York VQI. Females present at a later age with a different risk factors profile compared to males. However, following PTA the outcomes do not differ.
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